Karisma Injection

Home Dermatology Karisma Injection

Founded in 2014, Karisma’s main area of focus is to enhance collagen structure and function in the body. The aim is to help slow down the aging process, transitioning from pre-aging to anti-aging approaches. In essence, the work of Karisma injection lies in developing ways to keep the skin and other parts of the body youthful for as long as possible.

Product Overview

Karisma combines high molecular weight hyaluronic acid with the addition of the R-polypeptide chain α1 and carboxymethyl cellulose. The combination of these ingredients creates a product that can be both injected and resorbed by the body. This unique composition is designed to restore pre-aging conditions and rejuvenate the extracellular matrix. However, it is important to note that the rate at which Karisma is resorbed by the body varies depending on the individual. Some people may see results that last for several months, while others may see results that last for a year or more.

Function and Benefits of Karisma

As a bio-restitutive soft filler, Karisma is designed to naturally restore the body to its pre-aging conditions. It achieves this by acting on the rejuvenation of the extracellular matrix, a complex network of proteins and other molecules that provide structural and biochemical support to surrounding cells. By rejuvenating this matrix, it supports the overall health and youthfulness of the body’s tissues. Furthermore, the product’s specific dosage of its active substances is studied and calibrated to ensure their longevity and prolonged effect, thereby guaranteeing an extended period of effectiveness.

Impact of Karisma on Procollagen Production? 

Karisma Rh Collagen increases the production of Type I Procollagen C-Peptide in fibroblasts, which in turn promotes a triple helix conformation within the endoplasmic reticulum.

The Anti-Aging Benefits of Carboxymethylcellulose (CMC):

Carboxymethylcellulose helps keep the skin looking young and healthy by preventing the breakdown of hyaluronic acid in the skin, thereby allowing the skin to stay hydrated and repair itself more effectively.

Role of High Molecular Weight Hyaluronic Acid (HA):

High Molecular Weight Hyaluronic Acid (HA) creates an environment conducive to the proliferation and metabolism of fibroblasts, which are cells that produce collagen and other fibers.

The Natural Composition of Karisma Rh Collagen:

Karsima injection doesn’t use any chemical crosslinking agents.


The product’s biocompatibility promotes the skin’s natural regenerative ability.


Karisma’s non-allergenic properties and respect for the natural origin of the substances make it an unquestionably safe product. However, there is a small allergic reaction to Karisma, and it is important to consult with a healthcare provider before trying this injection.

Composition of Karisma 

The composition of the substance in the syringe is high molecular weight hyaluronic acid, with the addition of the R-polypeptide chain a1 and carboxymethyl cellulose.

This product is a pack, which contains:

One pre-filled 2ml glass syringe

Two 27-gauge, 1/2 needles

One leaflet ( for instructions or product information)

Two patient traceability labels


The Karisma injection should be performed at room temperature and under strict aseptic conditions, following the appropriate injection technique.

Call to Action

Karisma injection is used in a medical or clinical setting for cosmetic or therapeutic procedures, reiterating that you should consult a healthcare provider before trying this injection.

For more information and queries, please call Euromed Clinic by dialing +971 4 394 5422. You can also reach us by filling out and submitting the provided form.